SirtCore™ 01
Energy & Cellular Defense
The surgical alternative to AG1. Precision longevity for the European market.
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Four Precision-Dosed Compounds
Every ingredient at clinical dosage. No proprietary blends. No fillers. Full transparency.
Trans-Resveratrol
Sirtuin Activator
Direct SIRT1 activation, enhancing NAD+ utilization efficiency
Nicotinamide (Vitamin B3)
NAD+ Precursor
Direct substrate for NAD+ biosynthesis via the salvage pathway
EFSA Journal 2010;8(10):1757
"Contributes to normal energy-yielding metabolism"
Zinc Bisglycinate
Enzymatic Cofactor
Essential cofactor for 300+ enzymes including DNA repair
EFSA Journal 2009;7(9):1229
"Contributes to the protection of cells from oxidative stress"
Quercetin
CD38 Inhibitor
Inhibits CD38 enzyme that degrades NAD+, extending NAD+ half-life
The NAD+ Salvage Pathway
How SirtCore™ 01 optimizes your cellular energy metabolism through precision targeting
NAD+ Precursor Delivery
Nicotinamide enters cells and is converted to NAD+ via the salvage pathway enzyme NAMPT.
Sirtuin Activation
Trans-Resveratrol directly activates SIRT1 genes—the master regulators of cellular longevity and mitochondrial biogenesis.
NAD+ Protection
Quercetin inhibits CD38, the enzyme responsible for 95% of NAD+ degradation. This extends NAD+ half-life significantly.
Enzymatic Support
Zinc Bisglycinate serves as an essential cofactor for 300+ enzymes, including those in DNA repair and Sirtuin function.
The Result: Optimized NAD+ levels, enhanced mitochondrial function, and activated cellular defense mechanisms.
Precision vs. Kitchen Sink
See how targeted formulation compares to broad-spectrum approaches
| Feature | SirtCore™ 01 | AG1 | Seed DS-01 | Generic Multi |
|---|---|---|---|---|
| Ingredient Count | 4 (Precision) | 75+ | 24 | 20-30 |
| Precision Dosing | ||||
| EFSA Compliant | Full | Partial | Yes | Varies |
| Direct NAD+ Support | Yes (Nicotinamide) | Indirect | No | Minimal |
| Sirtuin Activation | ||||
| CD38 Inhibition | ||||
| Formula Transparency | Full Disclosure | Proprietary Blends | Full Disclosure | Varies |
| Price | €49 | €99 | €60 | €10-25 |
Why No NMN?
The science behind our regulatory-compliant approach
NMN (Nicotinamide Mononucleotide) is currently classified as a Novel Food in the European Union and has not received authorization for sale as a food supplement. While NMN shows promise in preclinical research, it cannot be legally sold in the EU market.
SirtCore™ 01 uses Nicotinamide (Vitamin B3), which is the scientifically validated and EU-authorized precursor that feeds directly into the NAD+ salvage pathway. Combined with Resveratrol for SIRT1 activation and Quercetin for CD38 inhibition, this stack delivers comprehensive NAD+ support through legal, proven ingredients.
References: EU Novel Food Regulation (EU) 2015/2283 • EFSA Journal 2010;8(10):1757 • EFSA Journal 2009;7(9):1229
GMP Certified
EU Manufacturing
Third-Party Tested
Independent Verification
Made in EU
Netherlands
EFSA Compliant
Full Documentation
Precision Longevity Starts Here
Four compounds. Clinical dosages. Full EU compliance. The surgical alternative to broad-spectrum supplementation.
Food Supplement. This product is not intended to diagnose, treat, cure, or prevent any disease. Manufactured in the EU in accordance with EFSA standards. Do not exceed recommended daily intake. Keep out of reach of children. Store in a cool, dry place. Consult your healthcare provider before use if you are pregnant, nursing, taking medication, or have a medical condition.