The Science · Biotechnology
Most supplements are destroyed before they can work. LipoSone™ is engineered to survive.
Standard oral supplements lose 80–95% of their active compounds to stomach acid and first-pass metabolism before reaching systemic circulation.
Moana Natura's LipoSone™ liposomal platform protects, transports, and delivers active compounds at a cellular level — using the same phospholipid bilayer architecture as your own cell membranes.
The Industry Problem
The EU supplement market generates €13.7 billion annually. The majority of that spend goes to products using conventional delivery formats — tablets, capsules, powders — that were never optimised for bioavailability. When you swallow a standard capsule, it enters a hostile environment: stomach acid at pH 1.5–3.5, digestive enzymes, and a mucus barrier designed specifically to prevent foreign molecules from entering systemic circulation.
For fat-soluble compounds — curcumin, CoQ10, vitamin D, glutathione — absorption in a standard oral dose is often below 10%. For water-soluble compounds undergoing hepatic first-pass metabolism, the picture is no better. The ingredient panel on the label may be accurate. What reaches your bloodstream is not.
Standard Capsule
Gastric Acid Exposure
pH 1.5–3.5 degrades unprotected compounds on contact
Enzyme Breakdown
Digestive enzymes cleave active molecules mid-transit
Mucus Barrier
Physical barrier limits epithelial contact surface
First-Pass Metabolism
Hepatic enzymes metabolise remaining compounds
< 10% Systemic Delivery
A fraction of the label dose reaches target tissues
LipoSone™ Liposomal
Phospholipid Encapsulation
Active compound sealed in a bilayer shell at 80–150nm
Acid-Resistant Transit
Shell stable at gastric pH — zero compound degradation
Epithelial Endocytosis
Cellular ingestion bypasses the transporter-saturation limit
Lymphatic Bypass
Enters systemic circulation without passing through the liver
Amplified Systemic Delivery
Up to 397× the bioavailability of standard oral form
The LipoSone™ Platform
Liposomes are spherical vesicles composed of one or more phospholipid bilayers — the same structural architecture as your body's own cell membranes. This technology has been used in pharmaceutical applications since the 1960s and is the delivery mechanism behind chemotherapy agents, antifungals, and IV-grade nutrient infusions. LipoSone™ is Moana Natura's proprietary implementation, manufactured under GMP conditions in Germany.
Active compounds are sealed inside a phospholipid bilayer — the same lipid structure as your cell membranes. Vesicle size is precisely controlled to 80–150nm for optimal epithelial penetration.
The phospholipid shell is chemically stable at gastric pH (1.5–3.5). Unlike unprotected molecules, encapsulated compounds traverse the stomach intact — zero compound degradation at this stage.
At the small intestinal epithelium, liposomes are taken up via endocytosis — a natural cellular ingestion mechanism — rather than passive diffusion. This bypasses the transporter-saturation limit of conventional absorption.
Liposomes enter the lymphatic system directly, bypassing hepatic first-pass metabolism. The compound is released into systemic circulation at concentrations no conventional oral dose can match.
OBV Comparison Data
Oral Bioavailability (OBV) multipliers represent the iAUC ratio of liposomal versus standard oral form. Data sourced from GMP-certified German production laboratory, 2018–2024.
Iron OBV vs. powder (397.7×) and vs. tablet with added Vitamin C (44.4×). All other OBVs from GMP-certified German production lab, 2018–2024. Data on file. Log scale — bars show relative proportions.
The Biology
Every cell in the human body is surrounded by a phospholipid bilayer membrane. This structural identity between liposomal shells and cellular membranes is not coincidental to why liposomal delivery works — it is the mechanism. When a liposome encounters a target cell membrane, it merges with it directly through membrane fusion, releasing its payload into the cytoplasm. No transporter. No diffusion gradient. No competing compounds for absorption bandwidth.
The phospholipids used in LipoSone™ are sourced from high-purity lecithin, standardised for phosphatidylcholine content — the dominant phospholipid in human cell membranes, with recognised biological roles in lipid transport and liver function.
Cell Membrane
Natural phospholipid bilayer surrounding every human cell
LipoSone™ Vesicle
Identical bilayer structure — active compound sealed inside at 80–150nm
Membrane Fusion
Liposome merges with cell membrane — direct cytoplasmic delivery
Production Standards
LipoSone™ formulas are manufactured exclusively in Germany, at a GMP-certified facility operating under EU Directive 2002/46/EC and EU Regulation 1169/2011. Good Manufacturing Practice is not a marketing term — it is a regulatory standard requiring validated equipment, documented processes, environmental monitoring, and independent batch testing at every production stage.
Manufacturing facility audited and certified under EU Good Manufacturing Practice. Batch records maintained for every production run.
Every batch undergoes independent testing for identity, potency, heavy metals (Pb, Cd, Hg, As), microbial load, and PCBs. Certificates of Analysis available on request.
Phosphatidylcholine standardised to ≥95% purity. No food-grade lecithin substitutes. No hydrogenated phospholipids.
Final vesicle size validated by dynamic light scattering (DLS) to 80–150nm — the optimal range for intestinal epithelial uptake and lymphatic absorption.
The Protocol
Every formula below uses LipoSone™ delivery as its bioavailability foundation.
White Mulberry DNJ · Chromium · EGCG
Reduced Glutathione (GSH)
Ferrous Bisglycinate
Curcumin Complex (95% curcuminoids)
Lion's Mane · Bacopa · Phosphatidylserine
Explore the full range of LipoSone™-delivered formulas — each clinically dosed, EFSA-compliant, and manufactured to pharmaceutical-grade standards in Germany.
This page describes delivery technology used in food supplements. Food supplements are not medicines and are not intended to diagnose, treat, cure, or prevent any disease. All health claims comply with EFSA Regulation 1924/2006. Manufactured in Germany in compliance with EU Directive 2002/46/EC.
